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One-pot Synthesis of Cinnamylamines with Various Protecting Groups from Cinnamyl Ethers

Archives of Pharmacal Research 2001³â 24±Ç 5È£ p.371 ~ 376
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Á¤¿µÈÆ ( Jung Young-Hoon ) 
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±èÁö´ö ( Kim Ji-Duck ) 
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Abstract


The reaction of various alkyl cinnamyl ethers with CSI afforded the corresponding cinnamylamines with various protecting groups, such as -NHMoc, -NHiPoc, -NHCbz, -NHPnz, -NHTroc and -NHAloc. In the case of cinnamyl t-butyl ether and cinnamyl p-methoxybenzyl ether, the corresponding cinnamyl carbamates were formed via a different reaction pathway from the above.

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Cinnamylamines;Chlorosulfonyl isocyanate;Alkyl cinnamyl ethers;Carbamates;Protecting group

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