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Acute-Onset Bilateral Myopia and Ciliochoroidal Effusion Induced by Hydrochlorothiazide

Korean Journal of Ophthalmology 2011³â 25±Ç 3È£ p.214 ~ 217
³ë¿µ·¡, ¿ì¼¼ÁØ, ¹Ú±ÔÇü,
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³ë¿µ·¡ ( Roh Young-Rae ) 
Seoul National University College of Medicine Department of Ophthalmology

¿ì¼¼ÁØ ( Woo Se-Joon ) 
Seoul National University Bundang Hospital Department of Ophthalmology
¹Ú±ÔÇü ( Park Kyu-Hyung ) 
Seoul National University Bundang Hospital Department of Ophthalmology

Abstract


The authors experienced two cases of hydrochlorothiazide (HCTZ)-induced acute-onset bilateral myopia and shallowing of the anterior chambers. Two middle-aged women taking HCTZ, a sulfa derivative, visited our clinic complaining of acute bilateral visual deterioration. Both had good visual acuity without corrective lenses before taking HCTZ. A complete ophthalmologic examination revealed bilateral myopic shift, intraocular pressure elevation, shallowing of the anterior chambers, choroidal effusions, radiating retinal folds, and conjunctival chemosis. Approximately one week after HCTZ discontinuance, all ocular changes disappeared completely. Physicians should be aware of the adverse ocular effects of HCTZ and should manage patients accordingly.

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Angle closure; Ciliochoroidal effusion; Drug-induced myopia; Hydrochlorothiazide; Myopia

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