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Fractional Flow Reserve: The Past, Present and Future

Korean Circulation Journal 2012³â 42±Ç 7È£ p.441 ~ 446
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±èÁ¤Àº ( Kim Jeong-Eun ) 
Seoul National University Hospital Department of Internal Medicine

±¸º»±Ç ( Koo Bon-Kwon ) 
Seoul National University Hospital Department of Internal Medicine

Abstract


Revascularization of coronary artery stenosis should be based on the objective evidence of ischemia. It is common practice for physicians to make decisions on revascularization in the cardiac catheterization laboratory based on the results of angiography, despite the fact that angiographic information does not correlate well with the functional significance of a coronary lesion. Fractional flow reserve (FFR) is a physiologic parameter which can be measured easily during the invasive procedure and can assess the functional significance of coronary stenosis. FFR-guided revascularization strategy is reported to be more effective than angiography-guided strategy in patients with coronary artery disease. Moreover, novel technologies based on FFR have been developed and will soon be incorporated into clinical practice.

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Coronary artery disease; Fractional flow reserve; myocardiol; Ischemia

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