Olanzapine 복용 이후 당뇨병 케톤산증이 발생한 정신분열병 환자
Diabetic Ketoacidosis in a Schizophrenic Patient Treated with Olanzapine: A Case Report.
신경정신의학 2005년 44권 1호 p.116 ~ 119
이중선, 김진용, 안준호, 김창윤,
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이중선 ( Lee Jung-Sun )
울산대학교 의과대학 서울아산병원 정신과학교실
김진용 ( Kim Jin-Yong )
울산대학교 의과대학 서울아산병원 정신과학교실
안준호 ( Ahn Joon-Ho )
울산대학교 의과대학 울산대학병원 정신과학교실
김창윤 ( Kim Chang-Yoon )
울산대학교 의과대학 서울아산병원 정신과학교실
KMID : 0368820050440010116
Abstract
The use of olanzapine has been associated with clinically significant hyperglycemia (exacerbation of existing diabetes, newonset type 2 diabetes and diabetic ketoacidosis). We report a case of diabetic ketoacidosis (DKA) in 30-year-old male patient with schizophrenia who was on olanzapine. When he was admitted to the hospital because of DKA, he had been taking olanzapine for 43 months. 14 months before the admission, his fasting and 2 hour postprandial serum glucose levels were normal. He had no personal and family history of diabetes mellitus. He had no risk factor for diabetes mellitus except for obesity (body mass index:39.2 kg/m2). He also had no precipitating factors for DKA such as infection or myocardial infarction. Periodic monitoring for changes in serum glucose levels in patients taking olanzapine may be needed.
키워드
Olanzapine;당뇨병 케톤산증;부작용
Olanzapine Diabetic ketoacidosis;Side effects
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