Severe Fever with Thrombocytopenia Syndrome Virus in Ticks in the Republic of Korea
강준구, 조윤경, 조영선, 한선우, 채정병, 박정은, 정혜성, 정원화, 채준석,
소속 상세정보
강준구 ( Kang Jun-Gu )
Chonbuk National University Korea Zoonosis Research Institute
조윤경 ( Cho Yoon-Kyoung )
Seoul National University College of Veterinary Medicine Laboratory of Veterinary Internal Medicine
조영선 ( Jo Young-Sun )
Seoul National University College of Veterinary Medicine Laboratory of Veterinary Internal Medicine
한선우 ( Han Sun-Woo )
Seoul National University College of Veterinary Medicine Laboratory of Veterinary Internal Medicine
채정병 ( Chae Jeong-Byoung )
Seoul National University College of Veterinary Medicine Laboratory of Veterinary Internal Medicine
박정은 ( Park Jung-Eun )
National Institute of Wildlife Disease Control and Prevention
정혜성 ( Jeong Hye-Sung )
National Institute of Wildlife Disease Control and Prevention
정원화 ( Jheong Weon-Hwa )
National Institute of Wildlife Disease Control and Prevention
채준석 ( Chae Joon-Seok )
Seoul National University College of Veterinary Medicine Laboratory of Veterinary Internal Medicine
Abstract
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a zoonotic, tick-borne RNA virus of the genus Bandavirus (Family Phenuiviridae), mainly reported in China, Japan, and the Republic of Korea (Korea). For the purpose of this study, a total of 3,898 adult and nymphal ticks of species Haemaphysalis longicornis (94.2%), Haemaphysalis flava (5.0%), Ixodes nipponensis (0.8%), and 1 specimen of Ixodes ovatus, were collected from the Deogyusan National Park, Korea, between April 2016 and June 2018. A single-step reverse transcriptase?nested PCR was performed, targeting the S segment of the SFTSV RNA. Total infection rate (IR) of SFTSV in individual ticks was found to be 6.0%. Based on developmental stages, IR was 5.3% in adults and 6.0% in nymphs. The S segment sequences obtained from PCR were divided into 17 haplotypes. All haplotypes were phylogenetically clustered into clades B-2 and B-3, with 92.7% sequences in B-2 and 7.3% in B-3. These observations indicate that the Korean SFTSV strains were closer to the Japanese than the Chinese strains. Further epidemiological studies are necessary to better understand the characteristics of the Korean SFTSV and its transmission cycle in the ecosystem.
키워드
Haemaphysalis longicornis; severe fever with thrombocytopenia syndrome virus; tick; National Park; vegetation; Korea
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