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Antioxidant Activities and Related Polyphenolic Constituents of the Methanol Extract Fractions from Broussonetia papyrifera Stem Bark and Wood

Food Science and Biotechnology 2010³â 19±Ç 3È£ p.677 ~ 682
Çã¸í·Ï, Wang Lan, Hu Jian-He, À̼®±â, ¿Õ¸íÇö,
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Çã¸í·Ï ( Xu Ming-Lu ) 
Henan Province Henan Institute of Science and Technology College of Chemistry Science

 ( Wang Lan ) 
Kangwon National University College of Biomedical Sciences
 ( Hu Jian-He ) 
Henan Province Henan Institute of Science and Technology College of Chemistry Science
À̼®±â ( Lee Soek-Ki ) 
Kangwon National University College of Medicine Department of Otolaryngology
¿Õ¸íÇö ( Wang Myeong-Hyeon ) 
Kangwon National University College of Biomedical Sciences

Abstract


Broussonetia papyrifera radix, fruits, leaves, and stems exhibit antioxidant, antinociceptive, antityrosinase, anti-inflammatory, and antiplatelet activities. However, study of the antioxidant activity of stem bark has been limited. In this work the antioxidant activity of stem bark and wood extracts were compared using different methods, and their phenolic constituents were analyzed. The bark ethyl acetate fraction exhibited the highest 2,2-diphenyl-2- picrylhydrazyl hydrate (DPPH) radical, hydroxyl radical scavenging activity, and the highest total phenolic and flavonoid contents. Both bark and wood n-butanol fractions showed stronger superoxide anion radical scavenging activity and reducing potential than other fractions. The bark and wood hexane fraction provided the highest level of ion chelating power. The high performance liquid chromatography (HPLC) analysis reveals there are more phenolic compounds in bark than in wood. These findings suggest that bark exhibits a higher antioxidant capacity than wood and that ethyl acetate and n-butanol fractions of B. papyrifera bark are potential natural resources for pharmacology of functional foods.

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Broussonetia papyrifera; bark; wood; antioxidant; high performance liquid chromatography (HPLC)

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