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Barrett Esophagus in Asia: Same Disease with Different Pattern

Clinical Endoscopy 2014³â 47±Ç 1È£ p.15 ~ 22
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ÀÌÇö¼® ( Lee Hyun-Seok ) 
Kyungpook National University School of Medicine Kyungpook National University Hospital Department of Internal Medicine

Àü¼º¿ì ( Jeon Seong-Woo ) 
Kyungpook National University School of Medicine Kyungpook National University Hospital Department of Internal Medicine

Abstract


Barrett esophagus (BE) is considered to develop as a result of chronic gastroesophageal reflux disease (GERD) and to predispose to esophageal adenocarcinoma (EAC). However, the disease pattern of BE in Asia differs from that observed in the West. For example, in the West, the prevalence rates of BE and EAC have progressively increased, whereas although the prevalence rate of GERD is increasing in Asia, the prevalence rates of BE and EAC have remained low in most Asian countries. GERD, hiatal hernia, old age, male sex, abdominal obesity (visceral obesity), smoking, alcohol consumption, and kyphosis are known risk factors for BE in Asia, and most Asian patients have shortsegment BE. Helicobacter pylori infection is more prevalent in Asia than in the West. We suggest larger studies with a prospective design be conducted to elaborate further the different patterns of BE in Asia.

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Barrett esophagus;Prevalence;Risk factors

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