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Evaluation of ultrasound point shear wave elastography reliability in an elasticity phantom

Ultrasonography 2022³â 41±Ç 2È£ p.291 ~ 297
Sultan Salahaden R., Alghamdi Amer, Abdeen Rawan, Almutairi Fahad,
¼Ò¼Ó »ó¼¼Á¤º¸
 ( Sultan Salahaden R. ) 
King Abdulaziz University Faculty of Applied Medical Sciences Department of Diagnostic Radiology

 ( Alghamdi Amer ) 
King Fahad Hospital Department of Diagnostic Radiology
 ( Abdeen Rawan ) 
King Abdulaziz University Faculty of Applied Medical Sciences Department of Diagnostic Radiology
 ( Almutairi Fahad ) 
King Abdulaziz University Faculty of Applied Medical Sciences Department of Diagnostic Radiology

Abstract


Purpose: To date, limited studies have specifically addressed the reliability of ultrasound point shear-wave elastography (pSWE). Therefore, the aim of the present study was to assess the reproducibility of ultrasound pSWE within and between operators using two ultrasound scanners.

Methods: iU22 and EPIQ7 ultrasound scanners were used to assess the reliability of pSWE measurements of four inclusions [L I (8 kPa), L II (14 kPa), L III (48 kPa), and L IV (80 kPa)] at a depth of 3.5 cm in an elasticity phantom using a curvilinear 5-1 MHz transducer. The intra-operator, inter-operator, and inter-scanner reproducibility of pSWE was assessed using intraclass correlation coefficients (ICCs). Bland-Altman plots were used to establish bias and limits of agreement (LoA) between measurements. The accuracy of pSWE from manufacturer values was determined using the one-sample t-test.

Results: Intra-operator agreement was excellent, with an ICC >0.90. The bias in measurements for operator A was -0.36¡¾3.13 kPa (LoA, -6.47 to 5.75), and for operator B it was 1.97¡¾6.29 kPa (LoA, -10.25 to 14.21). Inter-operator agreement was excellent, with an ICC of 0.95. The bias in measurements between operators was -0.42¡¾5.00 kPa (LoA, -10.24 to 9.38). The inter-scanner agreement between EPIQ7 and iU22 was excellent, with an ICC of 0.96. The bias in measurements between scanners was 1.74¡¾4.44 kPa (LoA, -6.95 to 10.45). There was significant overestimation for L I (17.75%) and L II (31.14%) and underestimation for L III (-15.28%) and L VI (-98.00%) relative to the manufacturer-reported values.

Conclusion: Phantom ultrasound pSWE was reproducible within and between operators, and between Philips ultrasound scanners; further studies using different ultrasound systems and transducers are required.

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Ultrasound; Point shear-wave elastography; pSWE; Elasticity phantom

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