대장 용종과 인슐린 저항성 및 당화혈색소의 관련성
The association between insulin resistance, glycated hemoglobin with the colorectal polyps
조은배, 곽태웅, 김보선, 김정은, 김진욱, 이경식, 조성민,
소속 상세정보
조은배 ( Jo Eun-Bae )
분당제생병원 가정의학과
곽태웅 ( Kwack Tae-Eung )
분당제생병원 가정의학과
김보선 ( Kim Bo-Seon )
분당제생병원 가정의학과
김정은 ( Kim Jeong-Eun )
분당제생병원 가정의학과
김진욱 ( Kim Jin-Wook )
분당제생병원 가정의학과
이경식 ( Lee Kyung-Shik )
분당제생병원 가정의학과
조성민 ( Cho Sung-Min )
분당제생병원 가정의학과
KMID : 1039620150050000158
Abstract
Background : The principal objective of the present study was to examine the association of insulin resistance and glycated hemoglobin level with the presenceofcolorectal polyps in subjects who underwent colonoscopy.
Methods : A total of 572 subjects were selected from among adults who underwent colonoscopy (age ≥ 30 years) at a health promotion center between September 1, 2013 and October 31, 2014. We evaluated body mass index, abdominal circumference, fasting glucose level, insulin level and glycated hemoglobin level. We also estimated the homeostasis model assessment insulin resistance index (HOMA-IR).
Results : The mean fasting glucose level, insulin level, HOMA-IR and glycated hemoglobin level were significantly higher in subjects with colorectal polyps(P<0.05). Logistic regression analysis showed that; insulin resistance(OR 1.51, 95% CI, 1.02-2.22) andglycated hemoglobin level (OR 3.93, 95% CI, 1.42-10.88) were significantly associated with the presence of colorectal polyps.
Conclusion : Insulin resistance and glycated hemoglobin level were closely related to the presence of colorectal polyps. Therefore, increased insulin resistance and glycated hemoglobin level could be prognostic factor to colorectal polyp’s prevalence.
키워드
Colorectal polyp; Insulin resistance; Glycated hemoglobin
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