Extracorporeal cardiopulmonary resuscitation among patients with out-of-hospital cardiac arrest
ÃÖ´ëÈñ, ±èÀ±Á¤, À¯½Â¸ñ, ¼Õâȯ, ¾È½Å, ¼µ¿¿ì, Lim Ju-Yong, ±è¿ø¿µ,
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ÃÖ´ëÈñ ( Choi Dae-Hee )
University of Ulsan College of Medicine Department of Emergency Medicine
±èÀ±Á¤ ( Kim Youn-Jung )
University of Ulsan College of Medicine Department of Emergency Medicine
À¯½Â¸ñ ( Ryoo Seung-Mok )
University of Ulsan College of Medicine Asan Medical Center Department of Emergency Medicine
¼Õâȯ ( Sohn Chang-Hwan )
University of Ulsan College of Medicine Asan Medical Center Department of Emergency Medicine
¾È½Å ( Ahn Shin )
University of Ulsan College of Medicine Department of Emergency Medicine
¼µ¿¿ì ( Seo Dong-Woo )
University of Ulsan College of Medicine Department of Emergency Medicine
( Lim Ju-Yong )
University of Ulsan College of Medicine Asan Medical Center Department of Thoracic and Cardiovascular Surgery
±è¿ø¿µ ( Kim Won-Young )
University of Ulsan College of Medicine Department of Emergency Medicine
KMID : 1100620160030030132
Abstract
Objective:Extracorporeal cardiopulmonary resuscitation (ECPR) may be considered as a rescue therapy for patients with refractory cardiac arrest. Identifying patients who might benefit from this potential life-saving procedure is crucial for implementation of ECPR. The objective of this study was to estimate the number of patients who fulfilled a hypothetical set of ECPR criteria and to evaluate the outcome of ECPR candidates treated with conventional cardiopulmonary resuscitation.
Methods:We performed an observational study using data from a prospective registry of consecutive adults (¡Ã18 years) with non-traumatic out-of-hospital cardiac arrest in a tertiary hospital between January 2011 and December 2015. We developed a hypothetical set of ECPR criteria including age ¡Â75 years, witnessed cardiac arrest, no-flow time ¡Â5 minutes, low-flow time ¡Â30 minutes, refractory arrest at emergency department >10 minutes, and no exclusion criteria. The primary endpoint was the proportion of good neurologic outcome of ECPR-eligible patients.
Results:Of 568 out-of-hospital cardiac arrest cases, 60 cases (10.6%) fulfilled our ECPR criteria. ECPR was performed for 10 of 60 ECPR-eligible patients (16.7%). Three of the 10 patients with ECPR (30.0%), but only 2 of the other 50 patients without ECPR (4.0%) had a good neurologic outcome at 1 month.
Conclusion:ECPR implementation might be a rescue option for increasing the probability of survival in potentially hopeless but ECPR-eligible patients.
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Out-of-hospital cardiac arrest; Cardiopulmonary resuscitation; Extracorporeal membrane oxygenation
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