Seroprevalence of antibodies to SARS-CoV-2 and predictors of seropositivity among employees of a teaching hospital in New Delhi, India
Sharma Pragya, Chawla Rohit, Bakshi Ritika, Saxena Sonal, Basu Saurav, Bharti Pradeep Kumar, Dhuria Meera, Singh S. K., Lal Panna,
소속 상세정보
( Sharma Pragya )
Maulana Azad Medical College Department of Community Medicine
( Chawla Rohit )
Maulana Azad Medical College Department of Microbiology
( Bakshi Ritika )
Maulana Azad Medical College Department of Community Medicine
( Saxena Sonal )
Maulana Azad Medical College Department of Microbiology
( Basu Saurav )
Maulana Azad Medical College Department of Community Medicine
( Bharti Pradeep Kumar )
Maulana Azad Medical College Department of Microbiology
( Dhuria Meera )
National Centre for Disease Control Division of Epidemiology
( Singh S. K. )
National Centre for Disease Control Division of Epidemiology
( Lal Panna )
Maulana Azad Medical College Department of Community Medicine
Abstract
Objectives: Healthcare workers (HCWs) are at a high risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) due to the increased likelihood of clinical exposure during patient management. The study objective was to determine the seroprevalence of antibodies to SARS-CoV-2 and its predictors among hospital employees.
Methods: The cross-sectional study was conducted at a teaching hospital from August 2020 to September 2020 among 1,401 employees, including 1,217 HCWs, in New Delhi, India. The serum samples were examined for immunoglobulin G (IgG) antibodies to SARS-CoV-2 using the COVID Kavach-Anti-SARS-CoV-2 IgG Antibody Detection enzyme-linked immunosorbent assay kit. Data were collected electronically using the EpiCollect mobile platform. A p < 0.05 was considered to indicate statistical significance.
Results: A total of 169 participants (12.1%) had detectable IgG antibodies to SARS-CoV-2. The highest seropositivity rate was observed in the administrative staff (20.1%), while it was lowest among medical doctors (5.5%, p < 0.001). Male sex and ever having lived in a containment zone were independently associated with past infection with SARS-CoV-2.
Conclusion: The seroprevalence of SARS-CoV-2 infection in health workers may be lower than in the general population in New Delhi. However, nonpharmaceutical interventions were not associated with a reduction in the risk of acquisition of SARS-CoV-2.
키워드
Communicable diseases; COVID-19; Occupational health
원문 및 링크아웃 정보
등재저널 정보