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Updated recommendations for the treatment of venous thromboembolism

Blood Research 2021³â 56±Ç 1È£ p.6 ~ 16
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È«ÁؽĠ( Hong Jun-Shik ) 
Seoul National University College of Medicine Seoul National University Hospital Department of Internal Medicine

¾È¼­¿¬ ( Ahn Seo-Yeon ) 
Chonnam National University Hwasun Hospital Department of Hematology-Oncology
ÀÌÀ¯Áø ( Lee Yoo-Jin ) 
University of Ulsan College of Medicine Ulsan University Hospital Department of Hematology and Oncology
ÀÌÁöÇö ( Lee Ji-Hyun ) 
Dong-A University College of Medicine Department of Internal Medicine
ÇÑÁ¤¿ì ( Han Jung-Woo ) 
Yonsei University College of Medicine Department of Pediatrics
±è°æÇÏ ( Kim Kyoung-Ha ) 
Soonchunhyang University College of Medicine Soonchunhyang University Seoul Hospital Department of Internal Medicine
ÀÓÈ£¿µ ( Yhim Ho-Young ) 
Chonbuk National University Medical School Chonbuk National University Hospital Department of Internal Medicine
³²½ÂÇö ( Nam Seung-Hyun ) 
Veterans Health Service Medical Center Department of Internal Medicine
±èÈñÁø ( Kim Hee-Jin ) 
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Laboratory Medicine and Genetics
¼ÛÀç¿ì ( Song Jae-Woo ) 
Yonsei University College of Medicine Severance Hospital Department of Laboratory Medicine
±è¼ºÇö ( Kim Sung-Hyun ) 
Dong-A University College of Medicine Department of Internal Medicine
¹æ¼ö¹Ì ( Bang Soo-Mee ) 
Seoul National University College of Medicine Seoul National University Bundang Hospital Department of Internal Medicine
±èÁø¼® ( Kim Jin-Seok ) 
Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
¹®¿µÃ¶ ( Mun Yeung-Chul ) 
Ewha Womans University College of Medicine Department of Internal Medicine
¹è¼ºÈ­ ( Bae Sung-Hwa ) 
Daegu Catholic University School of Medicine Department of Internal Medicine
±èÇö°æ ( Kim Hyun-Kyung ) 
Seoul National University College of Medicine Department of Laboratory Medicine
À强¼ö ( Jang Seong-Soo ) 
University of Ulsan College of Medicine Asan Medical Center Department of Laboratory Medicine
¹Ú³ëÁø ( Park Ro-Jin ) 
Soonchunhyang University Seoul Hospital Department of Laboratory Medicine
ÃÖÇü¼ö ( Choi Hyoung-Soo ) 
Seoul National University College of Medicine Seoul National University Bundang Hospital Department of Pediatrics
±èÀÎÈ£ ( Kim In-Ho ) 
Seoul National University College of Medicine Seoul National University Hospital Department of Internal Medicine
¿Àµµ¿¬ ( Oh Do-Yeun ) 
CHA University School of Medicine Department of Internal Medicine

Abstract


Venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis, is a condition characterized by abnormal blood clot formation in the pulmonary arteries and the deep venous vasculature. It is often serious and sometimes even fatal if not promptly and appropriately treated. Moreover, the later consequences of VTE may result in reduced quality of life. The treatment of VTE depends on various factors, including the type, cause, and patient comorbidities. Furthermore, bleeding may occur as a side effect of VTE treatment. Thus, it is necessary to carefully weigh the benefits versus the risks of VTE treatment and to actively monitor patients undergoing treatment. Asian populations are known to have lower VTE incidences than Western populations, but recent studies have shown an increase in the incidence of VTE in Asia. A variety of treatment options are currently available owing to the introduction of direct oral anticoagulants. The current VTE treatment recommendation is based on evidence from previous studies, but it should be applied with careful consideration of the racial, genetic, and social characteristics in the Korean population.

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Venous thromboembolism; Deep vein thrombosis; Pulmonary embolism; Anticoagulants

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