Analgesic effect of ropivacaine with fentanyl in comparison with ropivacaine alone for continuous femoral nerve block after knee replacement arthroplasty: a prospective, randomized, double-blinded study
김건희, 이준우, 김고은, 이성수, 손실리, 김병욱, 조하나, 권미영, 구민석, 김지은, 윤미정,
소속 상세정보
김건희 ( Kim Gunn-Hee )
National Medical Center Department of Anesthesiology and Pain Medicine
이준우 ( Lee Joon-Woo )
Seoul National University Bundang Hospital Department of Radiology
김고은 ( Kim Go-Eun )
National Medical Center Department of Anesthesiology and Pain Medicine
이성수 ( Lee Seong-Su )
National Medical Center Department of Anesthesiology and Pain Medicine
손실리 ( Son Shill-Lee )
National Medical Center Department of Anesthesiology and Pain Medicine
김병욱 ( Kim Byung-Uk )
National Medical Center Department of Anesthesiology and Pain Medicine
조하나 ( Cho Ha-Na )
National Medical Center Department of Anesthesiology and Pain Medicine
권미영 ( Kwon Mi-Young )
National Medical Center Department of Anesthesiology and Pain Medicine
구민석 ( Koo Min-Seok )
National Medical Center Department of Anesthesiology and Pain Medicine
김지은 ( Kim Ji-Eun )
National Medical Center Department of Anesthesiology and Pain Medicine
윤미정 ( Yun Mi-Jung )
National Medical Center Department of Anesthesiology and Pain Medicine
Abstract
Background: The analgesic effect of perineural opioid in clinical practice are still controversial. This randomized controlled trial compared analgesic effect of ropivacaine with fentanyl or ropivacaine alone for continuous femoral nerve block following unilateral total knee arthroplasty.
Methods: Fourty patients of ASA PS I or II receiving total knee arthroplasty with spinal anesthesia were enlisted and randomly allocated into two groups. Group R; bolus injection of 0.375% ropivacaine, 30 ml and an infusion of 0.2% ropivacaine at 8 ml/h (n = 20). Group RF; 0.375% ropivacaine, 29 ml added with 50 μg of fentanyl as a bolus and an infusion of 0.2% ropivacaine mixed with 1 μg/ml of fentanyl at 8 ml/h (n = 20). Local anesthetic infusion via a femoral nerve catheter was started at the end of operation and continued for 48 h. Intravenous patient-controlled analgesia with hydromorphone (0.15 mg/ml, 0-1-10) were used for adjuvant analgesics. Position of catheter tip and contrast distribution, visual analogue scale of pain, hydromorphone consumption, side effects were recorded for 48 h after operation. Patient satisfaction for the pain control received were noted.
Results: The pain visual analogue scale, incidences of side effects and satisfaction were not different between the two groups (P > 0.05), but the hydromorphone usage at 48 h after operation were lower in the Group RF than in the Group R (P = 0.047).
Conclusions: The analgesic effect of ropivacaine with fentanyl for continuous femoral nerve block after knee replacement arthroplasty was not superior to that of the ropivacaine alone.
키워드
Anesthesia and analgesia; Femoral nerve; Fentanyl; Nerve block; Ropivacaine
원문 및 링크아웃 정보
등재저널 정보