Thyroid Dysfunction Associated with Administration of the Long-Acting Gonadotropin-Releasing Hormone Agonist
한은진, 송하도, 양지훈, 박소영, 김성훈, 윤현구, 임창훈,
소속 상세정보
한은진 ( Han Eun-Jin )
Kwandong University College of Medicine Cheil General Hospital Department of Internal Medicine
송하도 ( Song Ha-Do )
Kwandong University College of Medicine Cheil General Hospital Department of Internal Medicine
양지훈 ( Yang Ji-Hoon )
Kwandong University College of Medicine Cheil General Hospital Department of Internal Medicine
박소영 ( Park So-Young )
Kwandong University College of Medicine Cheil General Hospital Department of Internal Medicine
김성훈 ( Kim Sung-Hoon )
Kwandong University College of Medicine Cheil General Hospital Department of Internal Medicine
윤현구 ( Yoon Hyun-Koo )
Kwandong University College of Medicine Cheil General Hospital Department of Internal Medicine
임창훈 ( Yim Chang-Hoon )
Kwandong University College of Medicine Cheil General Hospital Department of Internal Medicine
KMID : 0356620130280030221
Abstract
Gonadotropin-releasing hormone (GnRH) agonist has been used in the treatment of a wide variety of sex-hormone-related diseases, as the administration of GnRH agonist can alter the secretion of gonadotropin and sex hormones. Recently, we found that the long-acting GnRH agonist aggravated hyperthyroidism and induced painless thyroiditis. This is the first report to demonstrate the association of thyroid dysfunction with GnRH agonist injection in Korea. Here, we report three cases and emphasize the clinical importance of this aggravating factor in autoimmune thyroid disease.
키워드
Gonadotropin-releasing hormone agonist; Graves’ disease; Painless thyroiditis
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