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Graves¡¯ Disease that Developed Shortly after Surgery for Thyroid Cancer

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À¯Çý¹Î, Park Soon-Hyun, ÀÌÀç¹Î, ¹Ú°­¼­,
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À¯Çý¹Î ( Yu Hea-Min ) 
Eulji University School of Medicine Department of Internal Medicine

 ( Park Soon-Hyun ) 
Soe¡¯s Internal Medicine Clinic
ÀÌÀç¹Î ( Lee Jae-Min ) 
Eulji University School of Medicine Department of Internal Medicine
¹Ú°­¼­ ( Park Kang-Seo ) 
Eulji University School of Medicine Department of Internal Medicine

Abstract


Graves¡¯ disease is an autoimmune disorder that may present with various clinical manifestations of hyperthyroidism. Patients with Graves¡¯ disease have a greater number of thyroid nodules and a higher incidence of thyroid cancer compared with patients with normal thyroid activity. However, cases in which patients are diagnosed with recurrence of Graves¡¯ disease shortly after partial thyroidectomy for thyroid cancer are very rare. Here we report a case of hyperthyroid Graves¡¯ disease that occurred after partial thyroidectomy for papillary thyroid cancer. In this case, the patient developed hyperthyroidism 9 months after right hemithyroidectomy, and antithyroglobulin autoantibody and thyroid stimulating hormone receptor stimulating autoantibody were positive. Therefore, we diagnosed Graves¡¯ disease on the basis of the laboratory test results and thyroid ultrasonography findings. The patient was treated with and maintained on antithyroid drugs. The mechanism of the recurrence of Graves¡¯ disease in this patient is still unclear. The mechanism may have been the improper response of the immune system after partial thyroidectomy. To precisely determine the mechanisms in Graves¡¯ disease after partial thyroidectomy, further studies based on a greater number of cases are needed.

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Graves¡¯ disease; Partial thyroidectomy; Thyroid cancer; papillary

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