Co-Occurrence of Papillary Thyroid Carcinoma and Mucosa-Associated Lymphoid Tissue Lymphoma in a Patient with Long-Standing Hashimoto Thyroiditis
남윤정, 김보현, 이성근, 전윤경, 김상수, 정우진, 강동환, 김인주,
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남윤정 ( Nam Yoon-Jeong )
Pusan National University School of Medicine Pusan National University Hospital Department of Internal Medicine
김보현 ( Kim Bo-Hyun )
Pusan National University School of Medicine Pusan National University Hospital Department of Internal Medicine
이성근 ( Lee Seong-Keun )
I Sam Internal Medicine Clinic
전윤경 ( Jeon Yun-Kyung )
Pusan National University School of Medicine Pusan National University Hospital Department of Internal Medicine
김상수 ( Kim Sang-Soo )
Pusan National University School of Medicine Pusan National University Hospital Department of Internal Medicine
정우진 ( Jung Woo-Jin )
Pusan National University School of Medicine Pusan National University Hospital Department of Internal Medicine
강동환 ( Kahng Dong-Hwahn )
Pusan National University School of Medicine Pusan National University Hospital Department of Internal Medicine
김인주 ( Kim In-Ju )
Pusan National University School of Medicine Pusan National University Hospital Department of Internal Medicine
KMID : 0356620130280040341
Abstract
Papillary thyroid carcinoma (PTC) is a common affliction of the thyroid gland, accounting for 70% to 80% of all thyroid cancers, whereas mucosa-associated lymphoid tissue (MALT) lymphoma of the thyroid gland is uncommon. The simultaneous occurrence of both malignancies is extremely rare. We report the case of a patient with both PTC and MALT lymphoma in the setting of Hashimoto thyroiditis. An 81-year-old female patient was first admitted with goiter and hoarseness, which was attributed to an ultrasonographic thyroid nodule. Subsequent fine-needle aspirate, interpreted as suspicious of papillary thyroid cancer, prompted total thyroidectomy. MALT lymphoma was an incidental postsurgical finding, coexisting with PTC in the setting of Hashimoto thyroiditis. Although the development of MALT lymphoma is very rare, patients with longstanding Hashimoto thyroiditis should undergo careful surveillance for both malignancies.
키워드
Thyroid cancer; papillary; Lymphoma; B-cell; marginal zone; Hashimoto disease
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