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Treatment of Obstructive Colorectal Cancer
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À̵¿Èñ ( Lee Dong-Hee )
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ÀÌÀÎÅÃ ( Lee In-Teak )
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Á¤ºÀ¼ö ( Jung Bong-Soo )
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Á¤Ãá½Ä ( Jung Chun-Sik )
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±èâ³² ( Kim Chang-Nam )
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À¯Ã¢½Ä ( Yu Chang-Sik )
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±èÁøõ ( Kim Jin-Cheon )
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KMID : 0356719980140040751
Abstract
The occurrence of the colonic obstruction secondary to colorectal carcinoma (CRC) has been reported in 7¡30% of the CRC patients. It is generally believed that obstructive CRC is associated with a poor prognosis with respect to operative mortality and five-year survival. A series of 1064 cases of the CRC treated surgically at Asan Medical Center from June 1989 to December 1996 has been analyzed to compare clinicopathological findings between obstructive and non-obstructive CRC and to evaluate surgical treatment options in obstructive CRC. Complete obstruction was present in 49 cases (4.6%). There were no differences between obstructive and non-obstructive CRC in tumor location, size, Dukes¡¯ stage, and differentiation. In forty-nine obstructive CRC cases, primary resections were performed in 29 cases after peri-operative bowel decompression. In this group, right colon cancer was more prevalent than staged operation group (45% vs. 5%, P£¼0.05) and hospital stay was significantly short (16 days vs. 38 days, P£¼0.05). Postoperative complication rate was higher in staged operation group (65% vs. 28%, P=0.01). It may be due to stoma related wound complication. In obstructive left colon cancer, there was a significant difference in complication rate between primary resection and staged operation (P£¼0.05). Overall 5-year survival rate were 66% and 53% in non-obstructive and obstructive group, respectively. Survival rate according to the Dukes¡¯ B and C stages did not show statistical differences, either. Conclusively, primary resection is preferred to the obstructive CRC when supportive care, preoperative bowel decompression, and intraoperative colonic irrigation were performed adequately.
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Obstructive colorectal cancer;Primary resection
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