복강내 재발성 유건종에서 Tamoxifen, Goserelin 및 Sulindac을 이용한 병합 치료 2예
A Combined Treatment of Tamoxifen, Goserelin, and Sulindac in 2 Cases of Recurrent Desmoid Tumor in the Abdomen 2 Cases
김희철, 이동희, 안병율, 정춘식, 강경훈, 하현권, 하현권, 김진천,
소속 상세정보
김희철 ( Kim Hee-Cheol )
울산대학교 의과대학 외과학교실
이동희 ( Lee Dong-Hee )
울산대학교 의과대학 외과학교실
안병율 ( Ahn Byung-Yul )
울산대학교 의과대학 외과학교실
정춘식 ( Jung Chun-Sik )
울산대학교 의과대학 서울중앙병원 외과학교실
강경훈 ( Kang Gyung-Hoon )
울산대학교 의과대학 서울중앙병원 병리학교실
하현권 ( Ha Hyun-Kwon )
울산대학교 의과대학 서울아산병원 방사선과학교실
하현권 ( Ha HYUN-Gweon )
울산대학교 의과대학 서울중앙병원 진단방사선과학교실
김진천 ( Kim Jin-Cheon )
울산대학교 의과대학 외과학교실
KMID : 0356719990150040339
Abstract
Desmoid tumor is a subtype of fibromatosis arising from deep fascial or soft tissue structure. It is characterized by locally aggressive behavior with a tendency to local recurrence, but is generally accepted the lack of ability for distant metastasis. Although excision is the best initial therapy, surgery is not always amenable in cases of lesions lying
in difficult anatomical area. Two female patients with recurrent desmoid tumor in abdomen and pelvis after excision were treated with tamoxifen, goserelin, and sulindac. This therapy led to a progressive decrease of tumor size within 13 months in one patient. However, in the other patient, this combined therapy failed to reduce the size of the tumor. Despite the
success of combined therapy with hormone and nonsteroidal anti-inflammatory drug is anecdotal, this treatment may improve the survival and reduce the recurrence in certain sub-group of desmoid tumor.
키워드
Recurrent desmoid tumor;Tamoxifen;Goserelin;Sulindac
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