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Á÷Àå¿¡ ¹ß»ýÇÑ ¿ø¹ß¼º ¾Ç¼º Èæ»öÁ¾ Primary Malignant Melanoma of the Rectum

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À±½ÂÀç, ½Å¿ë¿î, Àåö¼ø, Á¶º´°ü, Á¶¿ë¹ü, À̵·, ±Ç¼º·Ä, ±èÇö¼®, ±Ç°è¼÷, Á¶Çö±Ù, ±è¹ü¼ö, ±è¿µ¼ö, ±è°æ·¡, ¹Î¼ö±â,
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À±½ÂÀç ( Yoon Seung-Jae ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç

½Å¿ë¿î ( Shin Yong-Woon ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Àåö¼ø ( Jang Chul-Sun ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Á¶º´°ü ( Jo Byung-Kwan ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Á¶¿ë¹ü ( Jo Young-Bum ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
À̵· ( Lee Don ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±Ç¼º·Ä ( Kwon Seong-Ryul ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±èÇö¼® ( Kim Hyun-Seok ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±Ç°è¼÷ ( Kwon Kye-Sook ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
Á¶Çö±Ù ( Jo Hyun-Keun ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±è¹ü¼ö ( Kim Pum-Soo ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±è¿µ¼ö ( Kim Young-Soo ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç
±è°æ·¡ ( Kim Kyung-Rae ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ ¿Ü°úÇб³½Ç
¹Î¼ö±â ( Min Soo-Kee ) 
ÀÎÇÏ´ëÇб³ ÀÇ°ú´ëÇÐ Çغκ´¸®Çб³½Ç

Abstract


Malignant melanoma arising from the mucosal surface is a rare, virulent malignant neoplasm frequently associated with an extremely poor prognosis. The sites of initial presentation include the nose, oral cavity, larynx, vulva, vagina, anal canal and rectum. Primary melanoma of the rectum is extremely rare and its histogenesis is controversial. We present a case of primary malignant melanoma arising from the rectum in a 77-year-old woman who presented with intermittent anal bleeding for 2 months. Colonoscopic examination of the rectum revealed a 3.5 3.0 2.7 cm exophytic tumor with a granular surface in the rectum, 5cm from the anal verge. Black colored pigmentation was detected. Distant metastasis to liver was detected on abdominal CT scan. Light microscopy of tumor revealed malignant melanocytes surrounded by normal mucosa. The tumor cells reacted positively for immunohistochemical staining with S-100 protein and HMB-45. Clinical and laboratory examination excluded the presence of melanoma at sites other than rectum. Local excision of the tumor was performed.

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Malignant melanoma

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KoreaMed
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