복막가점액종의 진단 및 치료방침
Diagnosis and Treatment Modalities in Pseudomyxoma Peritonei
이영진, 김희철, 이동희, 유창식, 김진천,
소속 상세정보
이영진 ( Lee Young-Jin )
울산대학교 의과대학 서울중앙병원 외과학교실 대장항문클리닉
김희철 ( Kim Hee-Chul )
울산대학교 의과대학 서울중앙병원 외과학교실 대장항문클리닉
이동희 ( Lee Dong-Hee )
울산대학교 의과대학 서울중앙병원 외과학교실 대장항문클리닉
유창식 ( Yu Chang-Sik )
울산대학교 의과대학 서울중앙병원 외과학교실 대장항문클리닉
김진천 ( Kim Jin-Chun )
울산대학교 의과대학 서울중앙병원 외과학교실 대장항문클리닉
KMID : 0356720010170030130
Abstract
Pseudomyxoma peritonei is an unusual condition in which gelatinous fluid collection is associated with mucinous implants on the peritoneal surfaces and omentum.
Purpose: The aim of this study was to evaluate the clinical characteristics of pseudomyxoma peritonei and elucidate the optimal treatment modality.
Methods: Nine patients (male：female=2：7) who had been operated on due to pseudomyxoma peritonei were analyzed retrospectively, in terms of clinical characteristics.
Results: The common symptoms and signs were abdominal pain, mass and distension. Elevated serum carcinoembryonic antigen (CEA) level was found in six cases. CT and ultrasonography were most valid diagnostic tools for pseudomyxoma peritonei. Six cases underwent debulking operation as initial treatment and two of them underwent intraoperative chemotherapy with 5-fluorouracil and other three cases did open biopsy. The origin of the primary tumor were appendix in three cases, ovary and appendix in three cases, ovary and colon in one case, ovary in one case, while the tumor origin could not be identified in one case. The three cases with cystadenoma remain free of disease after debulking operation. 2-Year survival rate of nine cases was 75%.
Conclusion: This study suggested that (1) the preoperative diagnosis could be made with careful physical examination in conjunction with sonography or computerized tomography; (2) the prognosis may be better in patient with benign origin and aggressive surgical management; (3) serum CEA level may be valuable for detection of this disease.
키워드
복막가점액종;암태아성항원;전산화단층촬영
Pseudomyxoma peritonei;CEA;Computerized tomography
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