재발성 대장암 진단에서 PET (Positron Emission Tomography)의 유용성
Clinical Usefulness of a PET Scan in the Diagnosis of a Recurrent Colorectal Carcinoma
박인자, 류진숙, 유창식, 김희철, 이강홍, 하현권, 김진천,
소속 상세정보
박인자 ( Park In-Ja )
울산대학교 의과대학 외과학교실
류진숙 ( Ryu Jin-Sook )
울산대학교 서울아산병원 핵의학교실
유창식 ( Yu Chang-Sik )
울산대학교 의과대학 외과학교실
김희철 ( Kim Hee-Cheol )
울산대학교 의과대학 외과학교실
이강홍 ( Lee Kang-Hong )
울산대학교 의과대학 외과학교실
하현권 ( Ha Hyun-Kwon )
울산대학교 의과대학 서울아산병원 방사선과학교실
김진천 ( Kim Jin-Cheon )
울산대학교 의과대학 외과학교실
KMID : 0356720040200020099
Abstract
Purpose: The aim of this study was to evaluate the potential efficacy of positron emission tomography using 2- [18F]-fluoro-2-deoxy-D-glucose in detecting recurrent colorectal carcinomas.
Methods: Seventy patients suspected of having recurrent colon cancer were evaluated using PET from January 2001 to March 2003. The PET results were compared with those of computed tomography and clinical examination over 6 months.
Results: Among the 70 patients, 17 patients had abnormal CEA levels and no abnormal findings with conventional radiologic methods (group 1), 29 had equivocal findings on computed tomography and other radiologic studies (group 2), and 24 were proven to have recurrent colorectal carcinoma (group 3) respectively. The sensitivity and the specificity of the PET scan, which were proved to be higher then those of CT (93% vs. 72.2%, 88% vs. 48.5%), were 85.7%, and 80%, respectively, in group 1, 86.7%, and 85.7% in group 2 and both 100% in group 3. The interval between diagnosis using PET and conventional studies was 1.9 months.
Conclusions: Positron emission tomography is more sensitive than computed tomography in detecting recurrent colorectal carcinomas. When conventional studies show no abnormal findings except for CEA levels, PET can be a valuable imaging tool in detecting recurrent colorectal cancer and can prevent other unnecessary exploratory procedures. J Korean Soc Coloproctol 2004;20:99-104
키워드
양전자방출단층촬영술;종양재발;민감도와 특이도
Positron emission tomography;Neoplasm recurrence;Sensitivity and specificity
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