원발성 맹장 림프종
Primary Cecal Lymphoma
박정훈, 신진용, 홍관희,
소속 상세정보
박정훈 ( Park Jung-Hoon )
인제대학교 의과대학 부산백병원 외과학교실
신진용 ( Shin Jin-Yong )
인제대학교 의과대학 부산백병원 외과학교실
홍관희 ( Hong Kwan-Hee )
인제대학교 의과대학 부산백병원 외과학교실
KMID : 0356720040200050283
Abstract
Purpose: Primary colonic lymphomas are very rare disorders and the most common location of a colonic lymphoma is the cecum. However, the prognosis for patients with a primary cecal lymphoma is not well understood clear. This
study was undertaken to assess the prognosis for patients with a primary cecal lymphoma.
Methods: A retrospective analysis of our patients, who were categorized into two groups, cecal lymphoma (10 cases) and non-cecal lymphoma (10 cases), was performed from January 1985 to December 2001. The prognostic factors were analyzed.
Results: The most common presenting symptoms and signs of cecal lymphomas were abdominal pain (80.0%), nausea/vomiting (80.0%), and abdominal mass (40.0%). The preoperative biopsy- proven diagnostic rate of cecal lymphoma was 10.0%. The mean size of cecal lymphomas was significantly smaller than that of non-cecal lymphomas (6.2 cm vs. 10.0 cm). Histologically, 9 (90.0%) of the primary cecal lymphomas were classified as intermediate-grade lymphoas, and 1 (10.0%) as a high-grade lymphoma. three (30.0%) of the cecal lymphomas were Stage IE, 5 (50.0%) were
Stage IIE1, and 2 (20.0%) were Stage IVE. Tumor resection and chemotherapy was used for 8 (80.0%) of the cecal lymphomas. Two regimens of chemotherapy were used:
CHEP-Bleo (cyclophosphamide, doxorubicin, and epirubicin, prednisone, and bleomycin) and COP-BLAM (cyclophosphamide, vincristine, prednisone, bleomycin, doxorubicin,
procarbazine). The median survival time for patients with a cecal lymphoma was 56 months, but that survival time was not significantly different from the survival time for
patients with non-cecal lymphoma.
Conclusions: The prognosis for patients with a primary cecal lymphoma
appears to be similar to that for patients with a non-cecal lymphoma. However, the number cases in our study was very small, the more cases are needed to establish a general prognosis for patients with a primary cecal lymphoma. J Korean Soc Coloproctol 2004;20:283-288
키워드
원발성 맹장 림프종;원발성 결장 림프종
Primary cecal lymphoma;Primary colonic lymphoma
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