Vienna 분류에 따른 한국인 크론병의 특징
The Characteristics of Crohn´s Disease in Korea according to the Vienna Classification
윤의상, 장연수, 이길연, 이석환, 윤충, 김효종,
소속 상세정보
윤의상 ( Yoon Eyi-Sang )
경희대학교 의과대학 외과학교실
장연수 ( Chang Yeon-Soo )
경희대학교 의과대학 외과학교실
이길연 ( Lee Kil-Yeon )
경희대학교 의과대학 외과학교실
이석환 ( Lee Seok-Hwan )
경희대학교 의과대학 외과학교실
윤충 ( Yoon Choong )
경희대학교 의과대학 외과학교실
김효종 ( Kim Hyo-Jong )
경희대학교 의과대학 내과학교실
KMID : 0356720050210050286
Abstract
Purpose: Crohn´s disease (CD) is a chronic inflammatory disease that is difficult to treat due to various complications and frequent recurrences. There have been many studies on the clinical aspects of CD in Western countries; however, there have been few studies in Korea. We performed this study to evaluate the clinical features of CD in Korea and to assess the stability over the course of the disease according to the Vienna classification.
Methods: We reviewed the medical records of 85 patients diagnosed as having CD in Kyung Hee University Hospital from March 1986 to July 2004.
Results: The male-to-female ratio was 1.9：1, and the mean age at diagnosis was 27.5 years. The most common symptom was abdominal pain (82%). Perianal lesions were observed in 29 cases (34%). Fistula was the most common (26%) lesion. Extraintestinal manifestations were observed in 13 cases (15%). Stomatitis was the most common (7%) lesion. According to the Vienna classification, the group with ages at diagnosis below 40 years (A1) was 88%, and that with ages equal to or above 40 years (A2) was 12%. The location of the disease was classified as terminal ileum (L1)(15%), colon (L2)(32%), ileocolon (L3)(33%), and upper gastrointestinal (L4)(20%). The behavior of disease was classified as nonstricturing nonpenetrating (B1)(41%), stricturing (B2)(14%), and penetrating (B3)(45%). Empirical anti-tuberculous medications were administered in 23 cases (27%) before the CD had been diagnosed.
Conclusions: There are differences in the locations and behaviors of Crohn´s disease between Korea and Western patients. The cause of the difference is uncertain. J Korean Soc Coloproctol 2005;21:286-292
키워드
크론병;비엔나 분류
Crohn´s disease;Vienna classification
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