대장 용종에서 거치상 선종의 임상적 특징
Clinical Features of Colorectal Serrated Adenomas
김형준, 김태효, 임병렬, 정경아, 김현진, 정운태, 주영태, 최상경, 이정희,
소속 상세정보
김형준 ( Kim Hyung-Joon )
경상대학교 의과대학 내과학교실
김태효 ( Kim Tae-Hyo )
경상대학교 의과대학 내과학교실
임병렬 ( Lim Byeong-Ryul )
경상대학교 의과대학 내과학교실
정경아 ( Jung Kyeong-A )
경상대학교 의과대학 내과학교실
김현진 ( Kim Hyun-Jin )
경상대학교 의과대학 내과학교실
정운태 ( Jung Woon-Tae )
경상대학교 의과대학 내과학교실
주영태 ( Ju Young-Tae )
경상대학교 의과대학 외과학교실
최상경 ( Choi Sang-Kyeong )
경상대학교 의과대학 외과학교실
이정희 ( Lee Jeong-Hee )
경상대학교 의과대학 병리학교실
KMID : 0356720060220020091
Abstract
Purpose: Colorectal cancer is believed to progress through an adenoma-carcinoma sequence. However, recent evidence increasingly supports the existence of an alternative route for colorectal carcinogenesis through a serrated adenoma, which combines the architectural features of hyperplastic polyps with the cytological features of traditional adenomas. We assessed the characteristics and the endoscopic features of serrated adenomas and compared them with those of hyperplastic polyps and traditional adenomas in Korea.
Methods: The medical records of 344 consecutive patients who underwent a colonoscopic biopsy or polypectomy from January 2003 through August 2004 at Gyeongsang National University Hospital were analyzed retrospectively.
Results: Serrated adenomas were seen in 12 cases (3.4%), and the most common site was the rectum (50%). Endoscopically in most cases, the serrated adenomas had small diameters (≤0.5 cm) and were single polyps. Morphologically, the serrated adenomas were flat and non- pedunculated. The coincidental rate of the carcinomas was 8.3%.
Conclusions: According to this study, serrated adenomas are generally single, sessile adenomas with diameters less than 5 mm, and they are commonly observed in the left colon, especially in the rectum. J Korean Soc Coloproctol 2006;22:91-96
키워드
거치상 선종;증식성 용종;전통적 선종;대장암
Serrated adenomas;Hyperplastic polyps;Traditional adenomas;Colorectal cancer
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