대장암 폐 전이
Lung Metastasis of Colorectal Cancer
김평수, 문선미, 황대용,
소속 상세정보
김평수 ( Kim Pyung-Soo )
원자력의학원 원자력병원 외과
문선미 ( Moon Sun-Mi )
한국원자력의학원 원자력병원 외과
황대용 ( Hwang Dae-Yong )
한국원자력의학원 원자력병원 외과
KMID : 0356720060220060380
Abstract
Purpose: The lung is the second most common site of metastasis of colorectal cancer. Pulmonary resection of lung metastasis of colorectal cancer has been reported a 5-year survival rate of 9∼57% variably. Therefore we have tried to assess the clinical patterns of lung metastasis from colorectal cancer and to evaluate prognostic factors.
Methods: A retrospective study was performed on 76 patients who presented with colorectal cancer with pulmonary metastasis between Jan. 1993 and Dec. 2001. Follow up period was 2∼92 months.
Results: 53 patients had developed pulmonary metastasis after curative resection of colorectal cancer, 27 patients of these cases showed isolated lung metastasis and 12 patients underwent pulmonary resection. The number of patients with single pulmonary nodule was 7 and they showed higher survival rate than those of multiple nodules (2-year survival rate: 80% vs. 33.3%, P=0.0325). The patients with normal serum CEA level showed higher survival rate than those with elevated serum CEA level (median survival-71 months vs. 32 months, P=0.0123) in 53 patients who had developed pulmonary metastasis after curative resection of primary tumor. The number of patients of TNM stage IV with synchronous lung metastasis was 23. And serum CEA level and the number of metastatic site had affected the survival in these cases.
Conclusion: The serum CEA level could be prognostic factors in pulmonary metastasis of colorectal cancer. And pulmonary resection for selected patients may improve the survival rate especially in the case which the number of metastatic nodule was only one. J Korean Soc Coloproctol 2006;22:380-386
키워드
대장암;폐 전이;예후인자;암태아성 항원
Colorectal neoplasm;pulmonary metastases;prognostic factor;Carcinoembryonic antigen
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