혈액질환 환자에서 발생한 대장암
Colon Cancer Secondary to Hematologic Disease
김도형, 이윤석, 지성배, 시윤, 강원경, 이인규, 오승택,
소속 상세정보
김도형 ( Kim Do-Hyoung )
항외과
이윤석 ( Lee Yoon-Suk )
가톨릭대학교 의과대학 성모병원 외과
지성배 ( Jee Sung-Bae )
가톨릭대학교 의과대학 성모병원 외과
시윤 ( Si Youn )
가톨릭대학교 의과대학 성모병원 외과
강원경 ( Kang Won-Kyung )
가톨릭대학교 의과대학 성모병원 외과
이인규 ( Lee In-Kyu )
가톨릭대학교 의과대학 성모병원 외과
오승택 ( Oh Seung-Teak )
가톨릭대학교 의과대학 성모병원 외과
KMID : 0356720090250040248
Abstract
Purpose: The incidence of secondary malignancies in hematologic patients is known to be higher than it is in other patients. However, the characteristics of secondary malignancy and surveillance have not yet been established for colorectal cancer in leukemic patients.
Methods: From 1995 to 2007, 6,030 patients who were diagnosed with acute myeloid leukemia (AML), acute lymphoid leukemia (ALL), chronic myeloid leukemia (CML), chronic lymphoid leukemia (CLL), and multiple myeloma (MM) were enrolled in this study. Among them, 9 patients were diagnosed with colorectal cancer at St. Mary’s Hospital and were analyzed retrospectively.
Results: Three of the 2,570 patients with AML, 1 of the 1,158 patients with CML, 2 of the 83 patients with CLL, 2 of the 422 patients with MM, and none of the 1,797 patients with ALL were found to have colorectal cancer. There were no operative mortalities, but 2 patients refused to have surgery. The ratio of observed to expected subsequent colorectal cancer in CLL was higher than it was in the other groups, indicating that the relative risk of colorectal cancer is higher in patients with CLL.
Conslusion: Compared to the Surveillance, Epidemiology and End-Result (SEER) program at the National Cancer Institute (NCI) in the United State, we have the same high relatively risk in CLL patients. Careful attention should be paid to the possibility of colorectal cancer in CLL patients.
키워드
대장암;백혈병;이차성암
Colorectal cancer;Leukemia;Secondary malignancy
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