결장 직장암에 의한 간 전이의 수술적 절제술의 효과
Outcomes of a Hepatic Resection for Colorectal-Carcinoma Liver Metastases
이우경, 김상범, 문선미, 조응호, 황대용,
소속 상세정보
이우경 ( Lee Woo-Kyoung )
한국원자력의학원 원자력병원 외과
김상범 ( Kim Sang-Bum )
한국원자력의학원 원자력병원 외과
문선미 ( Moon Sun-Mi )
한국원자력의학원 원자력병원 외과
조응호 ( Cho Eung-Ho )
한국원자력의학원 원자력병원 외과
황대용 ( Hwang Dae-Yong )
건국대학교 의과대학 외과학교실
KMID : 0356720100260030204
Abstract
Purpose: Recent managements of liver metastasis from colorectal cancer consist of multi-disciplinary treatments. Although hepatic resection is the only curative treatment, for which long-term survival is expected, the recurrence rates is still high. Recently, liver resections, combined with chemotherapy and other additional therapy, have produced promising outcomes. We analyzed the outcomes of hepatic resection for liver metastasis from colorectal cancer.
Methods: From 1993 to 2007, we performed 116 hepatic resections for the treatment of liver metastasis from colorectal cancer. All patients received adjuvant chemotherapy. We reviewed their medical records and investigated the clinico-pathologic data retrospectively.
Results: One in hospital mortality occurred, and the postoperative morbidity rate was 37.5%, including major complication (11.7%). Five-yr overall survival rate and disease free survival rate were 33.2% and 25.0%, respectively. T stage and postoperative morbidity were independent prognostic factors for survival whereas metachronous metastases and postoperative morbidity were independent prognostic factors for recurrence. During the follow-up periods, 67 recurrences occurred.
Conclusion: Hepatic resections for liver metastasis from colorectal cancer were safe and effective. The surgical T stage, complications, and metastasis type (metachronous or synchronous) may determine the results in patients with surgically-curable liver metastasis from colorectal cancer.
키워드
결장직장암;간 전이;간 절제술
Colorectal cancer;Liver metastasis;Hepatic resection
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