Clinical Features of Colorectal Cancer Detected by the National Cancer Screening Program
박대도, 신루미, 김지선, 오흥권, 정승용, 박규주, 박재갑,
소속 상세정보
박대도 ( Park Dae-Do )
Seoul National University College of Medicine Department of Surgery
신루미 ( Shin Ru-Mi )
Seoul National University College of Medicine Department of Surgery
김지선 ( Kim Ji-Sun )
Seoul National University College of Medicine Department of Surgery
오흥권 ( Oh Heung-Kwon )
Seoul National University College of Medicine Department of Surgery
정승용 ( Jeong Seung-Yong )
Seoul National University College of Medicine Department of Surgery
박규주 ( Park Kyu-Joo )
Seoul National University College of Medicine Department of Surgery
박재갑 ( Park Jae-Gahb )
Seoul National University College of Medicine Department of Surgery
KMID : 0356720100260060420
Abstract
Purpose: Since 2004, the National Cancer Screening Program of Korea has included colorectal cancer screening based on primary screening with the fecal occult blood test (FOBT). We report on the clinical features of colorectal cancer detected by the National Cancer Screening Program.
Methods: We retrospectively analyzed 577 patients who underwent elective surgery for colorectal cancer at the Seoul National University Hospital between January 2008 and December 2009. We compared the clinical features of colorectal cancers detected by the National Cancer Screening Program (NCSP group) with those of the control group in terms of age, gender, preoperative symptom, location of the tumor, surgical technique and tumor-node-metastasis (TNM) stage.
Results: Age, gender, location of the tumor and operation types were not different between the two groups. The proportion of asymptomatic patients was significantly higher in the NCSP group than it was in the control group (86.5% vs. 20.0%; P < 0.001). The proportion of less invasive lesions (T1 or T2) was significantly higher in the NCSP group (46.3% vs. 27.7%; P = 0.002). The pathologic stages of the colorectal cancers in the NCSP group were I, 40.3%; II, 17.9%; III, 40.3% and IV, 1.5% whereas in the control group, they were I, 20.8%; II, 32.9%; III, 34.9% and IV, 11.4%. The proportion of stage I cancer was significantly higher in the NCSP group than in the control group (40.3% vs. 20.8%; P = 0.006).
Conclusion: Our study demonstrates the FOBT in the NCSP is effective in early detection of colorectal cancer.
키워드
FOBT; National Cancer Screening Program
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