검안 시 급성심근경색 진단을 위한 심근효소 검사의 유용성
Evaluation of the Usefulness of Cardiac Enzyme Analysis for the Diagnosis of Acute Myocardial Infarction in Postmortem Inspection
박종필, 이탁수, 최민성, 양경무, 박정우, 원유진, 이종석, 김덕훈, 최승규, 이경홍, 김정환, 김모아, 유미영,
소속 상세정보
박종필 ( Park Jong-Pil )
연세대학교 의과대학 법의학과
이탁수 ( Lee Tak-Su )
국립과학수사연구원 서울과학수사연구소 법의조사과
최민성 ( Choi Min-Sung )
국립과학수사연구원 서울과학수사연구소 법의조사과
양경무 ( Yang Kyung-Moo )
국립과학수사연구원 중앙법의학센터
박정우 ( Park Jeong-Woo )
국립과학수사연구원 서울과학수사연구소 법의조사과
원유진 ( Won You-Jin )
국립과학수사연구원 서울과학수사연구소 법의조사과
이종석 ( Lee Jong-Seok )
국립과학수사연구원 서울과학수사연구소 법의조사과
김덕훈 ( Kim Duk-Hoon )
국립과학수사연구원 서울과학수사연구소 법의조사과
최승규 ( Choi Seung-Gyu )
국립과학수사연구원 서울과학수사연구소 법의조사과
이경홍 ( Lee Kyung-Hong )
국립과학수사연구원 서울과학수사연구소 법의조사과
김정환 ( Kim Jung-Hwan )
국립과학수사연구원 서울과학수사연구소 법의조사과
김모아 ( Kim Mo-A )
국립과학수사연구원 서울과학수사연구소 법의조사과
유미영 ( Yu Mi-Young )
경기남부경찰청
Abstract
Acute myocardial infarction is one of the most common causes of unexpected deaths, but there are limitations to its diagnosis in postmortem inspection. In this study, we aimed to investigate the usefulness of cardiac marker analysis for the diagnosis of acute myocardial infarction in postmortem inspection. This study was conducted on 30 postmortem inspection cases conducted by the National Forensic Service from 2016 to 2018. Tests for three myocardial enzymes (myoglobin, creatinine kinase-MB, and cardiac troponin I) were performed in each case, and the relationships between enzyme levels, cause of death, and factors affecting the postmortem tests were analyzed. Cardiac enzyme concentrations were not significantly different between the heart disease group and other disease groups, and the false-positive rate was increased due to postmortem changes. Therefore, we can conclude that it is not appropriate to use cardiac enzyme analysis for the diagnosis of acute myocardial infarction in postmortem inspection.
키워드
Myocardial infarction; Diagnosis; Postmortem changes; Troponin I
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