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Abstract


The authors isolated 27 organisms (11 species) from the patients, observed the
effective-ness of antibiophagine to the organisms in vitro, and compared the results with
the sensitivities to various antibiotics. .
The results were summarized as follows:
1. In vitro antibiophagine inhibited to a remarkable extent the growth of Salmonella
group D, E. coli, Shigella, Proteus and Enterobacter and inhibited moderately the growth
of Staphy-lococci and Salmonella group A.
2. When grossly negative growth on 24-hour culture subcultured, some strains of
Salmonella group D, E. coli, Shigella, Klebsiella and Proteus were not cultivated.
3. Some of Staphylococcus albus, Salmonella group A and Enterococcus which proved
resistant to the action of various antibiotics were sensitive to antibiophangine. A strain
of Staphylococcus aureus, not effective to antibiophagine, was sensitive to some
antibiotics.
4. Antibiophagine inhibited the growth of Pneumococcus and Enterobacter of which
bacteriophage are not contained in it.

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