韓國人 心性 肺動脈高血壓症의 肺血管 病變에 關한 病理組織學的 檢索
Vascular Changes in Congenital and Acquired Heart Diseases, Studied in Lung Biopsies of Koreans
소속 상세정보
함의근(咸毅根)/Eui Keun Ham
이현순(李賢淳)/Hyun Soon Lee
KMID : 0357919760100020181
Abstract
Histopathological investigation of lung biopsies on pulmonary vascular changes from 68
patients with congenital heart diseases and 58 with acquired heart diseases were made.
Used specimens were examined at the Department of Pathology, College of Medicine,
Seoul National University, during a period of 10 years from 1965 to 1974.
The progression of vascular changes in lung biopsies were so stereotyped as to allow
a division of structural effects into six grades regarding as Heath and Edwards method.
Author observed various gradational changes of pulmonary vascular lesions, ranging
from almost normal looking to marked medial hypertrophy with intimal fibrosis and
plexiform or angiomatous dilatation lesions. Intimal fibrosis was thought to be based on
organization of thrombi. One case of necrotizing angitis was revealed in a patient with
patent ductus arteriosus.
Severity of pulmonary vascular lesions of lung biopsies from patient with acquired
heart diseases was more prominent than those from patient with congenital heart
diseases. And no partiuclar relationships to sex was made from both groups of heart
diseases, but age had statistically significant relationship to those severity especially
inpatient group with congenital heart diseases (r=0.39, p<0. 01).
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