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ðÚòÄϹàõ ÍéâÐàõ ØÑßÒñø -2çÓ ÜÃͱ Histiocytic Medullary Reticulosis -Report of Two Cases

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¹é¿ÁÁö(ÛÜè¬ò«)/O. J. Paik Á¶Á¤ÀÚ(ðáïöí­)/¹®¼¼±¤(Ùþá¦ÎÃ)/C. C. Cho/S. K. Moon

Abstract


Two cases of histiocytic medullary reticulosis occurring in an 18 years old male and a
14 years old female were presented with discussion of their clinicopathologic
characteristics and brief literature review, and the latter was verified with autopsy.
Although the cutaneous lesions were much more prominent in our cases, the clinical
symptoms and signs, rapid fatal course, and hematological features were basically
identical to those of previously documented histiocytic medullary reticulosis.
On autopsy, the lesions were found to be systemic and showed diffuse proliferation of
the atypical hitiocytes engaged in active phagocytosis. Liver, spleen, Iymph nodes, and
bone marrow were mainly involved, but the other tissues, such as skin, lungs, brain,
kidneys, thyroid, adrenal capsule, pericardium, and thoracic wall, were considerably
affected as well.

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