성인에서 발생한 망막모세포종 1예 보고
A Case Report of Retinoblastoma in Adult
김한겸, 황적준, 정형목, 정지용,
소속 상세정보
김한겸 ( )
고려대학교 의과대학 임상병리과
황적준 ( )
고려대학교 의과대학 임상병리과
정형목 ( )
고려대학교 의과대학 임상병리과
정지용 ( )
고려대학교 의과대학 임상병리과
KMID : 0357919820160030504
Abstract
Retinoblastoma in an adult is extremely rare. This tumor is most common before the
age of two and rarely occur after the age o( seven. In 1929, Verhoeff reported a
well-documented retinoblastoma in a 48-year-old man. Since that report, about 17
additional crises have appeared in the world literature, but not in the domestic areas.
This case report is of a 67-year-old man whose enucleated right eye was found to
contain a retinoblastoma. It is believed to be the first recorded instance of
retinoblastoma in an adult in korea.
Grossly, the globe was a normal size and shape, measuring 26×25×25 ㎜. The cut
surface revealed two large grayish-white intraocular tumor masses in the temporal and
nasal area, measuring 19×12 ㎜ and 10×4 ㎜ in its extent, respectively. Microscopically,
the tumor consisted of round and oval hyperchromatic cells with scanty cytoplasm.
There were typical abundant Flexner-Wintersteiner rosettes, necrosis with multifocal
calcification, cholesterol clefts and foreign-body giant cells. The tumor invaded the
sclera, but the optic nerve was intact.
The pathogenesis of the retinoblastoma occuring in adults seems to be a late
development.
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