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Abstract

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The incidence of leiomyosarcoma of the small intestine was low, variably reported 1
to 3 per cent of all neoplasms of the gastrointestinal tracts and 10 to 14 per cent of all
cancers of the small intestine. We have recently experienced two cases of
leiomyosarcoma, one of which is located in the ileum from 63-year old female and the
other in the jejunum from 53-year old female. Grossly, the two tumor masses measured
7¡¿6¡¿5§¯ and 10 10 8§¯ in dimensions, respectively. There were areas of mucosal
ulceration and hemorrhage over the mucosa. The cut surface of the masses was
relatively wel1-demarcated, grayish white fibrous tissue with a few hemorrhagic
necrosis throughout the whole layers except for mucosa. Metastasis was found in the
retroperitoneum in one case and the liver in the other. Microscopically, both tumors
were composed of interlacing bundles of smooth muscle cells having increased cellularity
and atypical features. More than 6 mitoses per ten high power fields were found in both
tumors. The metastatic lesions were infiltrated with above neoplastic cells. 4 brief
review of literatures was made.

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