Behcet씨 증후군 환자 피부생검의 병리학적 및 면역병리학적 연구
A Pathologic and Immunopathologic Study of Behcet's Syndrome
정현주, 최인준,
소속 상세정보
정현주 ( )
연세대학교 치과대학 소아치과학교실
최인준 ( )
연세대학교 의과대학 병리학교실
KMID : 0357919850190030374
Abstract
The pathologic and immunopathologic findings of 15 skin biopsies of Behcet's
syndrome were studied to investigate the pathogenetic mechanism of this syndrome. The
age range was 28 to 50 years; male to female ratio was 1 : 1.2. Ulceration with acute
necrotizing and chronic nonspecific inflammation was present in most cases with
leukocytoclastic vasculitis and perivascular lymphohistiocytic, plasmocytic infiltrations.
Eight of 15cases showed C>3 deposit in the walls of venules and capillaries,
one of them was associated with IgM and fibrinogen deposits. With these findings
humoral factor seemed to play a main role in the pathogenesis of vasculitis observed in
Behcet's syndrome, but the possibility of other mechanisms operative in complex pattern
was also considered.
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