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Abstract

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Of 951 consecutive cases of liver biopsies reviewed, 162 cases were satisfied with
criteria of liver cirrhosis. Clinical records of the cirrhosis patients were summarized, and
morphologic as well as etiologic classifications on liver cirrhosis were attempted. The
morphologic and etiologic patterns characteristics in Korean were discussed in details
The following were results obtained ;
1) Posthepatitic cirrhosis was the most prevalent type in Korean classified as 120
cases of la2 cirrhosis patients (74.1%). Their morphologic types consisted of
micronodular (37 cases), mixed micro-and macro-nodular (48 cases), and macronodular
(34 cases) cirrhosis.
2) Alcoholic cirrhosis was presented as 11 cases of 162 cirrhosis (6.8% ), and
micronodular was the predominant type (9 cases) in alcoholic cirrhosis.
3) Secondary biliary cirrhosis due to congenital biliary atresia was presented in 5
children. The large duct obstruction with secondary biliary cirrhosis occurred in 14
cases. Causes of the large duct obstruction in adults were biliary stones, clonorchiasis
and inflammatory fibrosis of the bile ducts.
4) Cirrhosis of unpredictable etiology was noted in 12 cases, of which 10 cases were
classified as macronodular cirhosis.
5) Patients with posthepatitic and alcoholic cirrhosis were diagnosed mainly on needle
biopsy materials while those with secondary biliary cirrhosis were confirmed on the
wedge biopsy tissues obtained during a laparotomy.

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