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°ø³úÁõ (Porencephaly) -ºÎ°Ë 1¿¹ º¸°í- Porencephaly -An Autopsy Case Report

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±èÀμ÷/In Sook Kim ¼ÕÁøÈñ/¹ÚÈ¿¼÷/ÁöÁ¦±Ù/Jin Hee Shon/Hyo Sook Park/Je Geun Chi

Abstract


Porencephaly is a rare congenital anomaly characterized by a cavitary hole extending
from the cerebral mantle to the ventricle of the brain and covered by leptomeningeal
membrane. It is now generally believed that the porencephaly represents a fetal or
neonatal destructive process of the neural tissue.
Authors experienced an autopsy case of bilateral porencephaly in a 35-day-old Korean
male infant who died of sepsis. The brain weighed 150 ems and morphologically well
formed except for two large symmetric defects at the fronto-parietal region. These
defects were characterized by cleft-like shape, covering the entire cerebral mantle with
resultant direct communication between ventricular cavity and leptomeninges. Thin
leptomeningeal trabeculae were covering the cavity. There was a smooth transition
between ependyma and roof of the defects. There are focal, microscopic cerebral infarct
and abscess without connection with the cavitary lesion. The remaining central nervous
system was unremarkable.

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