유아의 흑색소성 신경외배엽성 종양 - 1증례보고 -
Malanotic Neuroectodermal Tumor of Infancy: A case report
주영채, 김준미, 황태숙, 김일규,
소속 상세정보
주영채 ( Chu Young-Chae )
인하대학교 의과대학 부속 인하병원 해부병리과
김준미 ( Kim Joon-Mee )
인하대학교 의과대학 부속 인하병원 해부병리과
황태숙 ( Hwang Tae-Sook )
인하대학교 의과대학 부속 인하병원 병리학교실
김일규 ( Kim Il-Kyu )
인하대학교 의과대학 부속 인하병원 치과학교실
KMID : 0357919920260050490
Abstract
The melanotic neuroectodermal tumor of infancy(MNTl) is a rare, usually benign, pigmented lesion which most frequently involves the maxilla. Skull, brain, and mandible are other craniofacial sites; this anatomic region accounts for 87% of all cases. The vast majority of MNTl, nearly 95%, present in infants of both sexes within the first year of life. Most cases of MNTl follow a benign course, with a 15% propensity for local recurrence. MNTl is regarded as a primitive neuroectodermal tumor with polyphenotypic differentiation. We report a classical MNTl which occurred in left lower maxilla in 6-month old female infant. She developed an ill defined, firm swelling on the left alveolar ridge and gum during 3 weeks. Mass excision reveals ill defined, grayish-tan hard mass, measuring 2.0x1.6 cm. Microscopically, the tumor reveals irregular alveolar pattern of melanin-containing cuboidal cells and nests of small round cells. The immunohistochemical staining for melanoma-associated antigen, neuron-specific enolase and cytokeratin show positive reactions. Ultrastructural examination showed intracytoplasmic melanosome, tonofilament and desmosome.
키워드
Melanotic neuroectodermal tumor of infantry; Retinal anlage tumor;
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