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±èÇöÁ¤/Hyun Jung Kim ±èµ¿¿ø/Áø¼Ò¿µ/À̵¿È­/Dong Won Kim/So Young Jin/Dong Wha Lee

Abstract

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Adenoid basal carcinoma of the uterine cervix is a rare neoplasm that accounts for
less than 1 % of cervical adenocarcinomas. Though it has been confused with adenoid
cystic carcinoma, it is now distinctly recognized by better prognosis and different
histologic and immunohistochemical findings. We have experienced a case of adenoid
basal carcinoma associated with invasive squamous cell carcinoma of the uterine cervix
in a 52-year-old woman. The tumor was composed of small, round to oval nests of
basaloid cells with peripheral palisading. Some of the nests showed central cystic spaces,
or cribriform pattern, and central squamous differentiation with cytological atypia.
Invasive squamous cell carcinoma was located adjacent to the adenoid basal carcinoma
without any transition between these two lesions. Immunohistochemically, the tumor
cells disclosed positive staining for cytokeratin, but negative reaction for CEA, EMA,
and 5-100 protein.

Adenoid basal carcinoma; Invasive squamous cell carcinoma; Uterine cervix; Immunohistochemical staining;

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