재발한 다형성 선종에서 발생한 악성 근상피종 - 1예 보고 -
Malignant Myoepithelioma Arising in a Recurrent Pleomorphic Adenoma - A case report -
정유경, 서연림,
소속 상세정보
정유경 ( Jeong Yu-Kyung )
조선대학교 의과대학 병리학교실
서연림 ( Suh Yeon-Lim )
성균관대학교 의과대학 삼성서울병원 진단병리과
KMID : 0357919990330070517
Abstract
Malignant myoepithelioma is a rare neoplasm of salivary gland which may either arise de novo or develop in a pre-existing pleomorphic adenoma. The malignant myoepithelioma occurs in 0.45% of major salivary gland tumors. Malignant myoepitheliomas arising in the pleomorphic adenoma number less than 20 in English literature and 1 in Korea. We describe a case of malignant myoepithelioma arising in a recurrent pleomorphic adenoma of the left parotid gland of a 61-year-old man. The tumor was ill-defined and composed of polygonal or plasmacytoid myoepithelial cells. Infiltration to surrounding tissue, hemorrhage, necrosis, increased mitotic activity and vascular tumor emboli indicated its malignant nature. There were several satellite nodules with histologic features of typical pleomorphic adenoma. Immunohistochemically, tumor cells were reactive for S-100 protein, AE1/AE3, vimentin, smooth muscle actin and glial fibrillary acid protein.
키워드
Malignant myoepithelioma;Pleomorphic adenoma;Parotid gland
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