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³­¼ÒÀÇ ´Ù³¶¼º ³­È²Á¾¾ç - 1¿¹ º¸°í - Polyvesicular Vitelline Tumor of the Ovary - A case report -

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¹®¿ì¼º, À̵¿±Ù,
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¹®¿ì¼º ( Moon Woo-Sung ) 
ÀüºÏ´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç ¹× ÀÇ°úÇבּ¸¼Ò

À̵¿±Ù ( Lee Dong-Geun ) 
ÀüºÏ´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç ¹× ÀÇ°úÇבּ¸¼Ò

Abstract


Polyvesicular vitelline tumor of the ovary is an extremely rare variant of yolk sac tumor. We present a case of pure polyvesicular vitelline tumor in a 43-year-old woman. Light microscopy revealed a predominantly polyvesicular pattern embedded in mesoblastic stroma with the cysts showing two type of lining; tall columnar and cuboidal, or mesothelioid cells. The lining atypical cells showed occasional mitoses and intracytoplasmic PAS positive hyaline globules. In some areas, the cystic space contained a large amount of intraluminal hyaline material. Immunohistochemically, alpha- fetoprotein and alpha-1-antitrypsin were detected as a fine granular deposit in the cytoplasm of epithelial cells and hyaline globules. Electron microscopically, marked specialization of the vesicular lining cells suggested a differentiation toward gut structures and mature yolk sac.

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Ployvesicular vitelline tumor;Yolk sac

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