신장의 유상피세포 혈관근지방종 - 1예 보고 -
Epithelioid Angiomyolipoma of the Kidney - A case report -
김유경, 이종실, 정기현, 박선후, 고경혁,
소속 상세정보
김유경 ( Kim Yu-Kyung )
경상대학교 의과대학 병리학교실
이종실 ( Lee Jong-Sil )
경상대학교 의과대학 병리학교실
정기현 ( Chung Ky-Hyun )
경상대학교 의과대학 비뇨기과학교실
박선후 ( Park Sun-Hoo )
경상대학교 의과대학 병리학교실
고경혁 ( Ko Gyung-Hyuck )
경상대학교 의과대학 병리학교실
KMID : 0357920000340110953
Abstract
Angiomyolipoma is considered by many authors to be a hamartoma, occurring in a sporadic form or in association with tuberous sclerosis. This lesion consists of thick walled blood vessels, smooth muscle, and mature adipose tissue in varying amounts. We have experienced a case of the angiomyolipoma composed of monotypic epithelioid cells. The patient was a 69-year-old female. Clinically, there was no evidence of tuberous sclerosis. Microscopically, the tumor was composed of polygonal cells with abundant eosinophilic granular or clear cytoplasm, pleomorphic nuclei, prominent nucleoli, and multinucleated giant cells. The tumor cells showed positive reaction for HMB45, CD68, smooth muscle actin, and S-100, and negative reaction for epithelial membrane antigen, cytokeratin, vimentin, desmin, CD34, estrogen receptor, and progesterone receptor. Ultrastructual analysis showed the presence of glycogen, mitochondria, and other microorganelles in neoplastic cells. Melanosome or premelanosome was not identified.
키워드
Epithelioid angiomyolipoma;Kidney
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