맥락총암종 - 2예 보고 -
Choroid Plexus Carcinoma - A Report of Two Cases -
심영란, 구미진, 김동석, 김오령, 변우목, 김용진,
소속 상세정보
심영란 ( Shim Young-Ran )
영남대학교 의과대학 병리학교실
구미진 ( Gu Mi-Jin )
영남대학교 의과대학 병리학교실
김동석 ( Kim Dong-Sug )
영남대학교 의과대학 병리학교실
김오령 ( Kim Oh-Lyong )
영남대학교 의과대학 신경외과학교실
변우목 ( Byun Woo-Mok )
영남대학교 의과대학 방사선과학교실
김용진 ( Kim Yong-Jin )
대구가톨릭대학교 의과대학 해부병리과
KMID : 0357920010350020176
Abstract
Choroid plexus carcinoma (CPC), a frankly malignant epithelial neoplasm derived from choroid plexus epithelium, is a rare tumor with a predilection for infants and children. It may be difficult to histologically differentiate it from choroid plexus papilloma, anaplastic ependymoma, medulloblastoma, germ cell tumors, and metastatic carcinoma. We examined two cases of CPC. One is a 12-month-old boy, and the other is a 13-month-old boy. Both patients present lateral ventricular masses with extensive hydrocephalus. Histologically, both tumors show papillary growth in most area, and focal solid growth. The tumor cells show marked nuclear pleomorphism and frequent mitoses on squash and hematoxylin-eosin slides. Immunohistochemically, both tumors are positive for cytokeratin, vimentin, and S-100 protein; but they are negative for glial fibrillary acidic protein, -fetoprotein, and placental alkaline phosphatase. Both tumors show diffuse and strong positivity for p53. The MIB-1 labelling index is 23.6% and 15.82%, respectively. We report two cases of typical CPC, and we briefly discuss differential diagnosis with review of literatures.
키워드
Brain;Choroid plexus neoplasms;Diagnosis;Differential;Immunohistochemistry
원문 및 링크아웃 정보
등재저널 정보