회음부의 세포성 혈관섬유종 - 3예 보고 -
Cellular Angiofibroma of the Vulva - A Report of Three Cases -
최혜정, 김성남, 김규래,
소속 상세정보
최혜정 ( Choi Hye-Jung )
울산대학교 의과대학 서울중앙병원 진단병리학교실
김성남 ( Kim Sung-Nam )
녹십자 임상검사센터
김규래 ( Kim Kyu-Rae )
울산대학교 의과대학 서울중앙병원 진단병리학교실
KMID : 0357920010350030259
Abstract
Cellular angiofibroma is a recently described, distinctive soft tissue tumor of the vulvovaginal region which is characterized by small, well-circumscribed tumors with fibroblastic differentiation. We report three cases of cellular angiofibroma of the
vulva in middle-aged women. All three patients presented with painless swelling in the labium majora. The age of the three patients ranged from 43 to 56 years old (mean: 48 years old) and the size of the tumor ranged from 2 to 5 cm. The microscopic appearance was characterized by a cellular, well-circumscribed mass composed of uniform, bland, spindle stromal cells, numerous thick-walled, hyalinized vessels, and a scarce component of mature adipocytes. Immunohistochemical stains of the tumor cells show positivity for vimentin but negativity for smooth muscle actin, S-100 protein, desmin, factor VIII-related antigen and epithelial membrane antigen. The tumor should be differentiated from aggressive angiomyxoma and angiomyofibroblastoma because of its different clinicopathologic features, cells of origin and immunohistochemical findings.
키워드
Angiofibroma;Vulva;Genitalia;Female
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