큰그물막의 원발성 위장관외간질종양 : 1예 보고
Primary Extragastrointestinal Stromai Tumor (EGIST) of the Greater Omentum : A Case Report
최경운, 설미영, 이창훈, 박도윤, 이준우, 서강석, 김지연,
소속 상세정보
최경운 ( Choi Kyung-Un )
부산대학교 의과대학 병리학교실
설미영 ( Sol Mi-Young )
부산대학교 의과대학 병리학교실
이창훈 ( Lee Chang-Hun )
부산대학교 의과대학 병리학교실
박도윤 ( Park Do-Youn )
부산대학교 의과대학 병리학교실
이준우 ( Lee Jun-Woo )
부산대학교 의과대학 진단방사선과학교실
서강석 ( Suh Kang-Suek )
부산대학교 의과대학 병리학교실
김지연 ( Kim Jee-Yeun )
부산대학교 의과대학 병리학교실
KMID : 0357920010350040347
Abstract
Gastrointestinal stromal tumors （GLSTs) were recently defined as spindle cell, epithelioid, or occasionally, pleomorphic mesenchymal tumors of the gastrointestinal tract that express the CD117 （proto-oncogene c-kit protein, stem cell factor receptor）, as detected using immunohistochemistry. And they show a new tendency to inciude the CD117-positie mesenchymal spindle cell or epithelioid neoplasms primary in the omentum and mesentery, and is so termed extragastrointestinal stromal tumors （EGLSTs）. Omental EGLSTs are very rare and similar to their gastrointestinal counterpart. We present a case of primary EGIST of the greater omentum in a 58-year-old man. The resected tumor mass measured 20×15×5㎝ and weighed 1,150g. The cut surface displayed a entral cystic change and partial mural nodules. Microscopically, most parts of the tumor were composed of round or polygonal cells, with many of them containing perinuclear vacuoles. The mitotic count was less than one per 50 high-powerfields. Immunohistochemically, the tumor cells were diffusely positive for CD117 and vimentin, and focally for smooth muscle actin and CD34. Ultrastructurally, partially smooth muscle differentiation was confirmed in this case.
키워드
Extragastrointestinal stromal tumor;Omentum;Proto-oncogene protein c-kit
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