이식후 림프증식성질환: 4예 보고
Posttransplant Lymphoproliferative Disorder: A Report of 4 Cases
장선희, 허주령, 김경모, 한덕종, 이승규, 유은실,
소속 상세정보
장선희 ( Chang Sun-Hee )
부천세종병원 해부병리과
허주령 ( Huh Joo-Ryung )
울산대학교 의과대학 서울중앙병원 진단병리학교실
김경모 ( Kim Kyung-Mo )
울산대학교 의과대학 서울중앙병원 소아과
한덕종 ( Han Duck-Jong )
울산대학교 의과대학 서울중앙병원 일반외과
이승규 ( Lee Sung-Gyu )
울산대학교 의과대학 서울중앙병원 일반외과
유은실 ( Yu Eun-Sil )
울산대학교 의과대학 서울중앙병원 진단병리학교실
KMID : 0357920020360010045
Abstract
Posttransplant lymphoproliferative disorder (PTLD) is a proliferation of B-cells associated with Epstein-Barr virr virus (EBV) infection as a complication of immunosuppression, especially by FK506. We investigated four cases of PTLD which developed either in allografts or in other organs. Case 1 was a 38-year-old woman, who developed monomorphic PTLD in a kidney 7 years and 7 months after renal transplantation. Case 2 was a 37-year-old man, who developed monomorphic PTLD in the right submandibular lymph node 4 months after liver tarnsplantation. Case 3 was a 60-year-old man, who developed monomorphic PTLD in the liver 8 months after liver transplantation. Case 4 was a 2-year-old female chile, who developed polymorphic PTLD in the colon, liver, and mesenteric lymph node 10 months after liver transplantation. FK506 was administered to case 4. EBV was identified in the tissues of all cases by immunohistochemistry and/or in situ hybridization.
키워드
Lymphoproliferative Disorders;Liver Transplantation;Kidney Transplantation
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