Ipsilateral Synchronous Renal Cell Carcinoma and Transitional Cell Carcinoma: A Case Report
박지영, 곽은경, 박태인,
소속 상세정보
박지영 ( Park Ji-Young )
성균관대학교 의과대학 삼성서울병원 병리학교실
곽은경 ( Kwak Eun-Kyung )
경북대학교병원 병리과
박태인 ( Park Tae-In )
경북대학교병원 병리과
KMID : 0357920020360060429
Abstract
We report a synchronous renal cell carcinoma (RCC) and renal pelvic transitional cell carcinoma (TCC) in the kidney of a 74-year-old man. The kidney was without hydronephrosis. The patient was admitted to the hospital because he had intermittent gross hematuria for three years. Histologically, a section of the specimen revealed a conventional (clear cell) RCC in renal parenchyma just beneath the renal pelvis and a papillary urothelial carcinoma arising from the renal pelvis at the upper pole; the two are completely separated from one another. The tumor cells of the TCC showed an overexpression of c-MET immunohistochemical staining and more intense positive reactivity for p53 immunohistochemical staining than those of the RCC. These findings suggest that c-Met and p53 may be associated with the development of papillary TCC.
키워드
Kidney Neoplasms;Carcinoma;Renal Cell-Carcinoma;Transitional Cell
원문 및 링크아웃 정보
등재저널 정보