Suprasellar Endodermal Sinus Tumor Presenting with Tonic-Clonic Seizure: An Autopsy Case Report
이민진, 구혜수, 한운섭, 성순희, 김용재, 최혜영,
소속 상세정보
이민진 ( Lee Min-Jin )
이화여자대학교 의과대학 병리학교실
구혜수 ( Koo Hea-Soo )
이화여자대학교 의과대학 병리학교실
한운섭 ( Han Woon-Sup )
이화여자대학교 의과대학 병리학교실
성순희 ( Sung Sun-Hee )
이화여자대학교 의과대학 병리학교실
김용재 ( Kim Yong-Jae )
이화여자대학교 의과대학 신경과학교실
최혜영 ( Choi Hye-Young )
이화여자대학교 의과대학 영상의학교실
KMID : 0357920020360060433
Abstract
We report the clinical course and autopsy findings of a 19-year-old girl with endodermal sinus tumor involving the thalamus, hypothalamus, and basal ganglia. The patient initially had tonic-clonic seizures with abnormal signal involving the right hippocampus, amygdala, basal ganglia, putamen, and dentate gyrus. The signal intensity of the posterior pituitary on T1-weighted images was decreased at the time of admission, which was not associated with clinical symptoms of diabetes insipidus (DI). A huge tumor mass as well as central DI developed within 10 months. The postmortem examination showed gliosis with calcification involving the right basal ganglia, internal capsule, and white matter, in addition to a tumor mass involving the thalamus, hypothalamus, and basal ganglia. Dissemination of tumor cells in the leptomeninges and the gliotic area and hydrocephalus were also noted.
키워드
Brain Neoplasms;Endodermal Sinus Tumor Wpilepsy;Tonic;Clonic
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