선천성 결합조직형성대뇌아교모세포종: 1예 보고
Congenital Desmoplastic Cerebral Glioblastoma: A Case Report
하홍일, 홍승모, 이승구, 강신광,
소속 상세정보
하홍일 ( Ha Hong-Il )
울산대학교 의과대학 서울아산병원 병리과
홍승모 ( Hong Seung-Mo )
울산대학교 의과대학 서울아산병원 병리과
이승구 ( Lee Seung-Koo )
울산대학교 의과대학 서울아산병원 병리과
강신광 ( Khang Shin-Kwang )
울산대학교 의과대학 서울아산병원 병리과
KMID : 0357920020360060440
Abstract
Desmoplastic cerebral glioblastoma has been described recently and is a very rare histologic variant of glioblastoma. We report a case of congenital cerebral glioblastoma associated with intense desmoplastic stromal reaction. A male infant was born at 36 gestational weeks by Cesarian section. He had a brain tumor, which was detected by fetal ultrasonography. The tumor was partially resected 2 months after the day of the boy´s birth and totally resected when he was one year old. The microscopic features of the tumor were those of glioblastoma, including high cellularity, frequent mitotic figures, vascular endothelial proliferation, and geographic palisading necrosis. The tumor showed an area of intense desmoplasia where tumor cells were surrounded by dense reticulin fibers. The desmoplastic cerebral tumors in children may be a distinct group of brain tumor, and it is important to understand the entity of these tumors which generally seem to be associated with more favorable prognosis compared to other high grade brain tumors.
키워드
Brain Neoplasms;Glioblastoma
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