폐의 염증성 근섬유모세포종(염증성 섬유육종) - 1예 보고 -
Inflammatory Myofibroblastic Tumor(Inflammatory Fibrosarcoma) of the Lung - A Case Report -
엄민섭, 김태헌, 박진규, 박광하, 정순희, 이광길,
소속 상세정보
엄민섭 ( Eum Min-Seob )
연세대학교 원주의과대학 병리학교실
김태헌 ( Kim Tae-Heon )
연세대학교 원주의과대학 병리학교실
박진규 ( Park Jin-Kyu )
연세대학교 원주의과대학 병리학교실
박광하 ( Park Kwang-Hwa )
연세대학교 원주의과대학 병리학교실
정순희 ( Jung Soon-Hee )
연세대학교 원주의과대학 병리학교실
이광길 ( Lee Kwang-Gil )
연세대학교 원주의과대학 병리학교실
KMID : 0357920030370040291
Abstract
Inflammatory myofibroblastic tumor, also known as inflammatory fibrosarcoma, has been frequently diagnosed as inflammatory pseudotumor. Although there are six cases reported as inflammatory pseudotumors or inflammatory myofibroblastic tumors in the lung, no cases of pulmonary inflammatory myofibroblastic tumor with features of inflammatory fibrosarcoma have been reported in Korea. We experienced a case of inflammatory myofibroblastic tumor (inflammatory fibrosarcoma ) characterized by high cellularity, severe nuclear pleomorphism, necrosis, or increased mitotic counts. A 31-year-old male patient with a solitary pulmonary nodule on the routine chest x-ray received a right lower lobectomy. The tumor was an ovoid solid mass with multifocal necrosis, showing diffuse irregular proliferation of spindle cells with high cellularity and focal nuclear pleomorphism, admixed with dense lymphoplasmacytic cells. Although spindle cells are focally immunoreactive for smooth muscle actin, the ultrastructural examination failed to demonstrate smooth muscle differentiation. In cases of inflammatory myofibroblastic tumor (inflammatory fibrosarcoma), a complete excision and close follow-up without radical surgery, radiation, or chemotherapy are needed.
키워드
Inflammatory Myofibroblastic Tumor;Inflammatory Fibrosarcoma;Inflammatory Pseudotumor;Lung
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